Latest CHEETAH Publication in BioMed Central Looks at Strategies to Minimise a Major Methodological Challenge in Cluster Randomised Controlled Trials (cRCTs)

The latest paper from the GSU’s recently completed CHEETAH trial discusses strategies to minimise and monitor biases and imbalances by arm in cRCTs

The recently conducted analysis includes 10,686 patients from 70 clusters with the study evaluating whether changing sterile gloves and instruments prior to abdominal wound closure reduces surgical site infection at 30 days postoperative. Eight strategies in total to minimise and monitor bias were pre-specified.

The paper identifies potential sources of bias when utilising cRCTs and looks at how the strategic system applied not only monitored and minimised the risks of bias and imbalances by arm but also highlights the lessons that can be learned for future cRCTs within hospitals.

You can access the publication by clicking here.

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